A novelty on the market from a Hungarian manufacturer, passed all tests and showed excellent quality both in analyzes and in practical application! A stable form of a liquid hormone that is not afraid of temperature changes, perfectly preserving its properties
Each vial contains: somatropin (recombinant human growth hormone) liquid form for subcutaneous injection.
Somatropin is a recombinant human growth hormone (rhGH) for injection. It contains an identical sequence of 191 amino acids to human growth hormone. Molecular formula C990H1528N262O300S7. Its molecular mass is 22,125 daltons. Each vial also contains 2 mg of medical glycine and 22 mg of medical mannitol.
Somatropin has the following pharmacological effects:
• Linear and skeletal growth (main action);
• Somatropin acts through specific growth hormone receptors, which are present in chondrocytes, osteoblasts, hepatocytes, adipocytes, and fibroblasts. These receptors are also found in other tissues, such as the brain and the gastrointestinal tract, where the role of growth hormone is unclear;
• Growth hormone stimulates the growth of the skeleton and soft tissues, promoting cell division, assimilation of amino acids and protein synthesis. Its action is mainly mediated by the production of hepatic and peripheral insulin-like growth factor-1 (IGFR-1), which leads to: - growth of the skeleton in children with growth hormone deficiency due to its effect on the epiphyseal growth zones of long bones; An increase in growth rate and IGF-1 level is observed, similar to that observed when taking human growth hormone; - increase in the number and size of muscle cells; - increase in the size of internal organs and mass of erythrocytes; - An increase in cellular protein synthesis due to nitrogen retention, which leads to a positive nitrogen balance, as evidenced by a decrease in urinary nitrogen excretion and blood urea nitrogen (BUN).
Somatropin also has the following effects: carbohydrate metabolism, lipid metabolism, mineral metabolism, connective tissue metabolism.
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