Peptides ACE-031 1 mg

ACE-031 

ACE-031 , also called ACVR2B or ActRIIB-IgG1, is a synthetically produced protein that was originally developed by two biopharmaceutical companies, namely Acceleron and Shire, for its potential ability to inhibit myostatin and other naturally occurring proteins that limit muscle growth. it is hypothesized that ACE-031 will act as a decoy receptor for catabolic proteins, in particular myostatin, and bind to them to keep them away from muscle fibers. Numerous studies have been conducted to determine whether ACE-031 is an effective treatment for children with Duchenne muscular dystrophy (DMD). 

What is myostatin?

Myostatin, abbreviated to GDF-8 (growth differentiation factor-8), is a protein naturally produced in mammals, which acts on muscle cells as an inhibitor of myogenesis (differentiation and growth of muscle cells). The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Li and Alexandra McFerron, who produced a strain of mutant mice in which the gene is missing.  scientists created a strain of mice that did not have the gene, and the muscle was about twice as large as normal mice.