Vesugen (Vesugen) bioregulator 20 mg

Vesugen - bioregulator and geroprotective tripeptide. Studies have shown that it protects the vascular system from the effects of aging, limiting the development of atherosclerosis and reducing the overall dysfunction of endothelial cells. Therefore, systems sensitive to vascular damage and decay demonstrate the most obvious effects from the introduction of Vesugen. Such systems include the central nervous system and the cardiovascular system. Vesugen, apparently, plays an important role in the regulation of the protein level of sirtuin 1. Sirtuin 1 has an important effect on metabolic processes and helps to reduce the consequences of aging. Sirtuin 1 is activated as a result of calorie restriction and is therefore considered one of the proteins responsible for the profound antiaging effects associated with calorie restriction

Vesugen
Vesugen (Lys-Glu-Asp) is a tripeptide with a beneficial effect on the vascular system. Since the vascular system is important in the whole body and in all metabolic processes, Vesugen has a wide-ranging effect. Studies show that it can improve the survival of neurons in the central nervous system, reduce atherosclerosis/restenosis by protecting blood vessels, and also increase cell survival and tissue health throughout the body. There is also research suggesting that Vesugen may play an important role in regulating addictive and reward-related behavior. Vesugen — this is an antiaging peptide, in part because it mimics some of the effects of calorie restriction.
It has long been believed that calorie restriction promotes longevity.

Vesugen 20 mg and brain

Vesugen — a promising neuroprotective peptide with potential application in the treatment of Alzheimer's disease. In past experiments, oral administration of the peptide to elderly people with functional disorders of the central nervous system (CNS) led to improved memory. It was also shown that the peptide restores synaptic plasticity, that is, the ability of neurons to create and strengthen connections between themselves.

Like most bioregulatory peptides, Vesugen apparently regulates the expression of genes involved in apoptosis and differentiation of neurons. Studies show that Vesugen affects genes p16, p21,
NES, GAP43, nestin, SUMO, APOE and IGF1. Some of these peptides are involved in apoptosis (programmed cell death) of neurons, while others are involved in the growth of neurons or, as has been shown, play a role in the pathogenesis of Alzheimer's disease.

Research also shows that such peptides as Vesugen, Epithalon, Pinealon and Violon can reduce the effects of hypoxia (lack of oxygen) in the central nervous system. Apparently, they do this by increasing the level of antioxidant enzymes and thereby helping to counteract the increase in the amount of neurotoxic active forms of oxygen that occurs when the level of oxygen decreases. According to Dr. Linkova, a Russian specialist in aging and gerontology, this effect of Vesugen can be useful not only in hypoxic events, such as a stroke or heart attack, but also in neonatal hypoxia during childbirth.

Vesugen and blood vessels

At least one of the reasons Vesugen protects the central nervous system is that it protects blood vessels from the clogging effects of atherosclerosis and therefore serves to maintain both the supply of nutrients to various tissues and the removal of waste products. The latter may be more important for long-term brain health, given that studies have shown that the brain produces large amounts of metabolic byproducts that, if not removed in time, they can be toxic to neurons.
Having a reliable blood supply helps ensure that neurons remain in a healthy environment. In fact, the main part (although not all) of the geroprotective effects of Vesugen can be reduced to its influence on vascular health.

Studies show that Vesugen is effective in the treatment of atherosclerosis and other cardiovascular diseases, especially in the elderly. It affects the expression of genes responsible for endothelium regulation and health. Endothelial cells — these are cells that line the inner part of blood vessels. Studies on mice show that Vesugen prevents the development of atherosclerosis and vascular stenosis (narrowing due to excessive growth of the endothelium) by normalizing the expression of endothelin and increasing the expression of sirtuin-1. Studies show that it promotes longevity, which means that Vesugen is, at least indirectly, an antiaging peptide.

Vesugen's ability to prevent lipid peroxidation (a process different from oxidation) increases the stability of erythrocyte membranes, which stabilizes the vascular network. This leads to a decrease in the percentage of dead cells circulating in the blood vessels (especially in the central nervous system), and may contribute to a decrease in the rate of apoptosis/necrosis.

Additional studies show that Vesugen stimulates the proliferation-related protein Ki-67 in blood vessels and that the level of Vesugen naturally decreases with age [5]. This suggests that, at least in part, the reason for the increase in vascular disease with age is not due to diet or environmental exposure, but simply that these cells begin to lose protective mechanisms as vesugene levels decrease.
Taking 20 mg of vesugen, which has been shown to be active when taken orally, may help prevent this age-related decline.

Vesugen and addiction

Studies show that sirtuin 1 is part of a large complex of proteins that regulate D1-type dopaminergic spiny neurons in the central nervous system. These neurons play an important role in the pathogenesis of addiction. These neurons play an important role in motivation, reward and habit formation. Dysfunction of these systems is associated with addiction and schizophrenia, as well as Parkinson's disease. The ability to regulate their function can become an important new tool in the treatment of various psychiatric and neurological disorders.

Summary of Vesugen

Vesugen is a bioregulator and geroprotective tripeptide. It protects the vascular system from the consequences of aging, limiting the development of atherosclerosis and reducing the general dysfunction of endothelial cells.
Therefore, systems sensitive to vascular damage and decline demonstrate the most obvious effects from the introduction of Vesugen. Such systems include the central nervous system and the cardiovascular system. Vesugen appears to play an important role in regulating the level of the protein sirtuin 1. Sirtuin 1 has an important effect on metabolic processes and helps reduce the effects of aging.
Sirtuin 1 is activated as a result of calorie restriction and is therefore considered one of the proteins responsible for the profound antiaging effects associated with calorie restriction.