B7-33 has a strong antifibrotic effect. It is actively researched and used as a means to reduce fibrosis in acute and chronic diseases such as heart failure, pneumonia, kidney disease, etc.
In animal studies, B7-33 reduced fibrosis by approximately 50%, which led to increased life expectancy after trauma and offered the first new treatment for heart failure in 20 years.
It has been shown to reduce excessive scarring after heart failure injuries It has also shown promise in the treatment of some vascular diseases, as well as preeclampsia during pregnancy.
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