Bronchogen (Bronchogen) bioregulator 20 mg

Bronchogen - you can buy it in our online store. It is a bioregulatory peptide with tissue-specific action in the lungs. Studies in rats show that bronchogen can reduce inflammation and restore lung tissue health by affecting several DNA transcription pathways. The ultimate effect of Bronchogen on the lungs is to improve the condition of the epithelium, increase the production of surfactant, and reduce inflammation.
Research continues, studying the use of Bronchogen not only in diseases, but also in aging.
It seems that Bronchogen has a geroprotective effect, helping to reverse the age-related decline in lung function by reactivating aging DNA. The peptide may even prove to be useful, helping to reveal ways to protect against the development of lung cancer.

Bronchogen (Ala-Glu-Asp-Leu) is a DNA-stabilizing peptide with a length of only four amino acids [1]. Studies show that it acts as a bioregulator, especially in lung tissue, stimulating the growth, proliferation and differentiation of certain cell lines. In particular, bronchogen appears to increase the levels of certain DNA transcription factors and reverse the age-related decline in DNA transcription. The peptide has been investigated for its ability to treat certain lung diseases, as a possible plant growth factor, and as a geroprotective agent against aging.
Like many bioregulators, Bronchogen appears to play an important role in the regulation of the inflammatory response.

Fundamental studies using microcalorimetric measurements show that DNA in the presence of bronchogen has a higher melting point than DNA otherwise. This may seem like a trivial fact, useful only in a few very specific technical laboratory protocols, but in fact this conclusion has a wider meaning. Studies of DNA stability have shown that the higher the stability of DNA, the less its degradation occurs over time and the less telomerase is activated.
Microcalorimeter measurements are an excellent indicator of DNA stability in real conditions.

It may seem counterintuitive that telomerase activation can sometimes be a bad thing. After all, telomerase protects telomeres and prevents cell aging due to too short chromosomes. Although this is true, telomerase activity is also associated with an increased risk of cancer. This is due to the fact that under certain conditions, DNA damages accumulate and these damages induce telomerase activity. This leads to two problems. First, the DNA repair process is not ideal, and therefore the lengthening of telomeres in some cases can actually interfere with the normal mechanisms of apoptosis, which will rid the body of cells containing aberrant DNA. The second problem is that a high level of telomerase activity is necessary only with high cell turnover. Thus, high telomerase activity is actually a marker of rapid aging.
Thus, while telomerase is good, the fact that you have to use it is actually not so good because it indicates rapid cell turnover and potentially increased DNA damage.
In short, the balance between telomerase activity and DNA health is fine. In an ideal world, telomerase would be activated less often, because the DNA would remain healthier and, therefore, the enzyme would not be needed as often.

Stabilizing DNA, Bronchogen reduces the amount of damage it inflicts over time and reduces the rate of cell renewal. These features, in turn, reduce the need for telomerase activity. What is even more important is that it allows the DNA to remain healthy longer, thus preventing cells with unhealthy DNA from going into a state of senescence or even apoptosis. The final result is a reduction in aging and an improvement in the general condition of the tissues, since the cells remain healthy for longer periods of time and ultimately preserve the limited ability of all human tissues to regenerate from stem cells.

Bronchogen as a growth factor

Studies on rat skins show that Bronchogen and similar peptides have a stimulating effect even in very low concentrations on recovery processes. This effect appears to be mediated by an increase in the number of CXCL12 and Noch factors, both of which are transcription factors that regulate cascades affecting growth and differentiation. It is interesting that the effects of these transcription factors are more pronounced in old cell lines than in younger cell lines. The older the cells are, the more benefit they receive from the introduction of bronchogen, as the growth and differentiation of cells increases, which leads to an improvement in the health and functioning of tissues.

Bronchogen in the lungs

The main effects of Bronchogen, as indicated above, are growth and differentiation. Due to the tissue specificity of Bronchogen, these effects are limited primarily to lung tissue. Studies in rats show that bronchogen is very effective against certain diseases, such as chronic obstructive pulmonary disease (COPD) and asthma, in the lungs. Bronchogen helps to prevent and facilitate the remodeling that occurs in these diseases by improving the aberrant immune response that causes hyperplasia, dysplasia and death of ciliated cells. It also reduces the level of pro-inflammatory cytokines, reducing the level of inflammation in the lungs and helping to prevent scarring and fibrosis.

Perhaps, most importantly, studies on rats show that
Bronchogen can restore lung epithelium after induction of COPD and other inflammatory diseases. This leads to an increase in surfactant production and a decrease in alveolar surface tension. This means that Bronchogen acts directly on the causal process of the progression of the disease in the lungs, and does not simply treat the symptoms. By increasing the production of surfactant, Bronchogen literally increases the ability of the lungs to exchange oxygen and carbon dioxide in the blood. By restoring epithelial cells, such as ciliated cells, Bronchogen helps the lungs to efficiently distribute surfactant and remove debris and toxins.

Bronchogen as a plant hormone

One relatively unusual aspect of Bronchogen is that it is active in plants at a very low concentration.
one relatively unusual aspect of Bronchogen is that it is active in plants at a very low concentration.
Studies show that Bronchogen together with Epithalon increases the growth and regeneration of plant tissues by activating several regulatory pathways, including the CLE pathway, transcription factors KNOX1 and GRF (regulatory factors growth), which bind to DNA and regulate transcription. This work, although interesting for botanists, also emphasizes the function of bronchogen as a DNA regulatory factor controlling growth, proliferation and differentiation

Brief description of bronchogen

Bronchogen — bioregulatory peptide with tissue-specific action in the lungs. Studies in rats show that bronchogen can reduce inflammation and restore lung tissue health by affecting several DNA transcription pathways. The final effect of Bronchogen on the lungs is an improvement in the condition of the epithelium, an increase in the production of surfactant and a decrease in inflammation. Studies are ongoing, studying the use of bronchogen not only in diseases, but also in aging. It seems that Bronchogen has a geroprotective effect, helping to reverse the age-related decline in lung function by reactivating aging DNA. The peptide may even prove to be useful, helping to reveal ways to protect against the development of lung cancer.