Peptides IGF1 DES 1mg

IGF1 DES

Insulin-like growth factor (IGF)-1 (4-70), also known as IGF-1 DES, produced in E.coli, is a single non-glycosylated polypeptide chain containing 67 amino acids and having a molecular weight of 7,372 Da. Studies in vitro show that at equal doses of DES (1-3) IGF is ten times more effective than IGF-1, at stimulation of hypertrophy and proliferation in cultured cells. It is probably generated by means of post-translational modification in the sequence of circulating mature IGF-1 through the action of a protease. IGF-1 DES is a cleaved form of IGF-1 and contains amino acids 4-70. This structure made it possible to enhance the action of the IGF-1 protein in a more stable form of a peptide protein fragment of the DES 1,3 molecule insulin-like growth factor 1. DES IGF-1 or insulin-like growth factor DES comes from the IGF-1 family of peptides, which play an important role in the growth and development of mammals. IGF1 mediates many of the growth-stimulating effects of growth hormone and IGF-1 DES, although shorter, provides an equal amount of physiological changes to physical changes in the protein. Early studies have shown that growth hormone does not directly stimulate the incorporation of sulfate into cartilage, but acts through serum factor called "sulfation factor", which later became known as "somatomedin".